Can you help us learn more about the body’s immune response to COVID-19 vaccines?
The Platform Trial In COVID-19 Vaccine BOOsting (PICOBOO) Study is designed to evaluate the comparative effectiveness of COVID-19 booster vaccines.
The Kids Research Institute Australia researchers are working with study sites around Australia to see what effect COVID-19 booster vaccination has on the immune system, how long these effects last, and what the optimal booster strategies are for people living in Australia. The study will also explore the safety of booster vaccination and how well boosting protects against hospitalisation and disease.
Your participation in the PICOBOO Study will help researchers develop the most effective, long-term strategies for COVID-19 booster vaccinations nation-wide.
What does the study involve?
To participate in the PICOBOO study, adults will need to attend five visits over a one-year period, while adolescents will have four visits over a six-month period. The visits will take place at research clinics located in Perth, Adelaide, or Launceston.
These appointments will include:
- randomised vaccination with one of the two latest COVID-19 XBB.1.5 booster vaccines
- providing blood and saliva samples to test for an individual's immune response before they receive their vaccine and at three or four additional time points over the study period.
- completing SMS surveys (taking 2 – 5 minutes) daily for 7 days after the vaccine visit, at Day 28, and every three months for up to 2 years to assess any COVID-19 symptoms, medical visits, or disruptions to work, study, or daily activities.
Are you eligible to participate?
Study researchers are urgently seeking the following participants:
- Adolescents aged 12 to 17 - who have had two doses of Pfizer or Moderna as their primary vaccine and haven’t received a booster in the last three months.
- Adults aged 50 to 69 - who have had two doses of Pfizer or Astra Zeneca as their primary vaccine and haven’t received a booster in the last three months.
- Adults aged 70 and above - who received Astra Zeneca as their primary vaccine and haven’t received a booster in the last three months.
Participating Research Clinics
To find your nearest research clinic and register your interest, please refer to the information provided below:
Perth
The Kids Research Institute Australia
Perth Children’s Hospital
15 Hospital Avenue
Nedlands, WA, 6009
Register Here: https://redcap.link/PICOBOOinterestregister
Contact: Vax4COVID@telethonkids.org.au
Adelaide
Adelaide Women’s and Children’s Hospital
72 King William Rd
North Adelaide, SA, 5006
Register Here: https://redcap.link/PICOBOOAdelaide
Contact: VIRTU@adelaide.edu.au
Launceston
Launceston General Hospital
274-280 Charles St
Launceston, TAS, 7250
Register Here: https://redcap.link/PICOBOOTasmania
Contact: Research@cliffordcraig.org.au
Further information
For further information about the study, please visit https://picoboo.com.au.
This study has been approved by the Child and Adolescent Human Research Ethics Committee. Any person with concerns or complaints about the conduct of this study should contact the Executive Director Medical Services via [08 6456 2222] who can refer your concerns to the HREC monitoring the project.